There’s 11 games in Saturday and 4 on Sunday for MLS Week 2. Let’s get into 6 games, in 3 parlays for this weekend’s MLS best bets.
MLS Picks #1
Two Saturday games both in the early slot at 2:30pm EST.
Chicago Fire vs CF Montreal Prediction
Both lost in Week 1, but for Chicago it was just 2-1 to Houston, while CF Montreal were routed 5-0 in San Diego. A 50’ red card from defender Avilas obviously didn’t help matters. He’ll miss out here.
Last year the teams drew 1-1 in Chicago and the Fire won 2-0 in Montreal.
Montreal didn’t add much this offseason and it could be another long year.
The Fire’s top scorer Cuypers got off the mark last week with their 1 goal, and they added some nice pieces with Lod in the midfielder and South African international Mbokazi on defense.
There’s a big gap in talent between these teams and I think Chicago should win and likely score a couple of goals while doing so.
- MLS Picks: Chicago to win
New York Red Bulls vs New England Revolution Prediction
The NYRB started 3 players 17 and younger and won 2-1 vs Orlando, with Hall getting 2 goals and Mehmeti 1 assist. Orlando’s 1 goal also came late-on in stoppage time.
New England are missing some defenders and it showed, getting pumped 4-1 in Nashville on Week 1.
The last 2 times this matchup was in New York, the Red Bulls won 4-2 and 5-3. In between, New England has win of 1-0 and 2-1 at home, meaning a road team has now won in 9 meetings.
- Soccer Picks: NYRB to score
- Parlay: CHI to win / NYRB to score (-127)
MLS Picks #2
Houston Dynamo vs LAFC Prediction
LAFC could not have asked for a better start to 2026. Last week they dominated Miami winning 3-0 in LA. In the CCC, they won 6-1 and 1-0 over Real Espana to move on. The Leg 2 match vs Espana also allowed them to rest key starters later in the game.
Off the field, while it once looked like superstar Bouanga could be on his way out at some point this year, the club announced they’ve resigned him through 2028 on Wednesday.
Houston also started with a win, getting an 11-minute brace from new DP signing Guilherme, beating Chicago 2-1. Guilherme joined this offseason from Santos, meanwhile they added some more players from the south, with Bogusz from Cruz Azul (an ex-LAFC player too) and bringing back Hector Herrera from Toluca. Already having Ponce up top, they look improved from last season.
Last year both won at home, Houston 1-0 and LAFC 2-0. This hasn’t been a high-scoring matchup with BTTS NO going 7-0 and Under 2.5 going 6-0.
- MLS Picks: BTTS
FC Dallas vs Nashville SC Prediction
Both got high-scoring wins in Week 1, Nashville 4-1 over New England and Dallas 3-2 over Toronto.
Nashville has also had a couple of good wins over lower level side Atletico Ottawa in the CCC, winning 2-0 and then 5-0 this week in Leg 2.
The Yotes look loaded for a good season, already with 2 of the leagues top scorers in Surridge and Mukhtar, and adding Espinoza from San Jose. Last week Surridge came out flying with 2 goals, and Mukhtar had 1 too. New signing Madrigal also got on the scoresheet so it’s all good news in Music City.
Dallas has a star of their own in Musa, and he too had a big Week 1 with a brace vs TFC.
- Soccer Picks: BTTS
- Parlay Picks: HOU vs LAFC btts / DAL vs NAS btts (+158)
MLS Picks #3
Orlando City SC vs Inter Miami CF Prediction
Maybe the marquee match of the weekend is between two teams that lost in Week 1— Orlando 2-1 at home to a young Red Bulls side, but they could’ve conceded even more giving up almost 5 xG, while Miami lost 3-0 on the road to LAFC.
Miami reloaded this offseason with new players all over the lineup, highlighted by Monterrey’s Berterame. He had just 1 shot attempt last week and Messi 4, neither putting any on target. Allende had 9 playoff goals last year so if he gets the start, could be worth a prop bet.
Meanwhile, Orlando were more sellers, transferring Freeman, Muriel and Gallese. They still have Pasalic and Ojeda who combined for 32G/24A last season in all matches. New winger Tiago made an instant contribution getting Orlando’s lone goal last week.
Both teams had big home wins last year—4-1 for Orlando and 3-1 for Miami. A road team has only won 2 of the past 13 matchups in this Florida Derby.
- MLS Picks: BTTS and Over 2.5
San Diego FC vs St. Louis City SC Prediction
San Diego already advanced in the CCC beating Pumas 4-2 over two legs, so they were full focused on their Week 1 match last week and they routed Montreal by a 5-0 score, and they got goals from 4 different players and 2 from Ingvartsen.
St. Louis got the season started with a 1-1 draw hosting Charlotte. They outshot Charlotte 22-9, forcing Kahlina into 10 saves, but the Crown didn’t push forward much.
They drew San Diego in California 0-0 last year but lost at home 2-1 later on.
- Soccer Picks: San Diego double chance
- Parlay Picks: ORL vs MIA btts & Over 2.5 / SD double chance (-114)
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Ryan Métivier is a seasoned editor, writer and communications professional with years of experience in all fields. When it comes to covering sports, he’s written for numerous outlets and organizations including the OHL, CHL, SportsXpress, Sports Betting Dime, Cleveland.com, MassLive, FanSided and others.
While he’ll always cheer for his hometown Toronto teams, when it comes to betting, his only allegiance is his bankroll. Ryan specializes in global soccer, the NFL and the NHL, but if there is a bet to be made, he’ll make it. As the founder of Shred The Spread, Ryan focuses on combining storylines, trends, analytics and good bankroll management to creating simple bets that make sense.
When not making a case for why both teams will score in an MLS soccer match, he can be found focusing his efforts on fitness, attempting to learn Spanish, cooking or planning his travel adventure.
